A Secret Weapon For ceesdekker.net
A Secret Weapon For ceesdekker.net
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Nanotechnology offers a range of options to lead to biology. Listed here I'll current illustrations wherever nanofabrication – a chance to make confined buildings with Proportions at will – is used to look at the biophysics of one molecules and cells. I will existing some examples from our lab:
But how do morality, the dignity of your individual, my expertise from the this means of lifetime, stick to within the movement of atoms? A purely naturalistic perspective fails below; a Christian viewpoint, I think, is a way more affordable solution to interpret these facets of reality.’
Dynamics of initiation, termination and reinitiation of DNA translocation with the motor protein EcoR124I
Non-equilibrium folding of particular person DNA molecules recaptured as many as one thousand moments in the stable condition nanopore
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Our study ranges from your biophysics of DNA to synthetic cells and beyond. Make sure you have a look below at the spectrum of our current projects.
What distinguishes biology from chemistry is these factors collectively make up a living technique. The secret of explained lifestyle, I feel, lies within the interactions, the interaction of those molecules. The large dilemma in regards to the origin of lifestyle remains to be unanswered. How did we at any time evolve from straightforward molecules into the very complicated methods we see now? We have no idea. I need to operate on These types of huge, open queries.’
Stream-pushed rotary motors like windmills and water wheels generate useful procedures in human society. Even though examples of these kinds of rotary motors also element prominently in mobile biology, their artificial construction in the nanoscale has remained tough. Listed here we display move-pushed rotary movement of the self-structured DNA nanostructure that may be docked onto a nanopore in a thin sound-condition membrane. An elastic DNA bundle self-assembles into a chiral conformation upon phoretic docking onto the strong-state nanopore, and subsequently displays a sustained unidirectional rotary motion of up to 20 rev s−one.
The rotors harness Vitality from the nanoscale drinking water and ion movement that is created by a static chemical or electrochemical prospective gradient within the nanopore, which are recognized through a salt gradient or used voltage, respectively. These artificial nanoengines self-organize and run autonomously in physiological situations, suggesting ways to developing Power-transducing motors at nanoscale interfaces.
It was for the duration of this era that Dekker performed research on magnetic spin techniques and on sound in superconductors and semiconductors.
An integrated microfluidic platform for quantifying drug permeation across biomimetic vesicle membranes
1999, first measurement on the wavefunction of single molecular orbitals of carbon nanotubes; and discovery of kink https://www.ceesdekker.net heterojunctions of carbon nanotubes which gave decisive proof for a new Luttinger description of interacting electrons in nanotubes
Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of only one wire bridging two electrodes
Lastly, I will briefly sketch a few of our Concepts to examine the setting up of artificial cells, specifically our first actions to establish synthetic cell division.